According to the NCI website, thioguanine is a synthetic guanosine analogue antimetabolite. Phosphorylated by hypoxanthine-guanine phosphoribosyltransferase, thioguanine incorporates into DNA and RNA, resulting in inhibition of DNA and RNA syntheses and cell death. Check for active clinical trials using this agent. (NCI Thesaurus)

Indikationen/Anwendungsmöglichkeiten gemäss Compendium®

• Akute myeloische Leukämie.
• Lanvis kann auch zur Behandlung der akuten lymphatischen Leukämie angewendet werden.

Link zur Fachinformation von Compendium.ch®:

Merkblätter für Patientinnen und Patienten

More Information in English:

Link to Drug Information Portal, a service of the U.S. National Library of Medicine, National Institutes of Health

Link to MedlinePlus, a service of the U.S. National Library of Medicine, National Institutes of Health
Link to National Cancer Institute

Wiki

Link zu PharmaWiki

Info for Patients presented by Scott Hamilton from Chemocare.com