According to the NCI website, Pevonedistat is a small molecule inhibitor of Nedd8 activating enzyme (NAE) with potential antineoplastic activity. Check for active clinical trials using this agent. (NCI Thesaurus)

July 30st: Pevonedistat was granted breakthrough therapy designation by the FDA as a treatment for higher-risk myelodysplastic syndromes

More Information in English:

Inxight: Drugs (NIH)

AdisInsight

Link to Drug Information Portal, a service of the U.S. National Library of Medicine, National Institutes of Health

Link to MedlinePlus, a service of the U.S. National Library of Medicine, National Institutes of Health
Link to National Cancer Institute

Wiki
Link to European Medicines Agency (EMEA)