Orvacabtagene autoleucel
According to the NCI website, Orvacabtagene autoleucel (autologous anti-BCMA-CAR-4-1BB-CD3zeta-expressing CD4+/CD8+ T lymphocytes JCARH125) is an immunoconjugate consisting of the humanized monoclonal antibody M9346A against folate receptor 1 (FOLR1) conjugated, via the disulfide-containing cleavable linker sulfo-SPDB, to the cytotoxic maytansinoid DM4, with potential antineoplastic activity. Check for active clinical trials using this agent. (NCI Thesaurus)
Inxight: Drugs (NIH)