Estramustine - ESTRACYT®
According to the NCI website Estramustine and its major metabolite estramustine bind to microtubule-associated proteins (MAPs) and tubulin, thereby inhibiting microtubule dynamics and leading to anaphase arrest in a dose-dependent fashion.
Indikationen/Anwendungsmöglichkeiten gemäss Compendium®:
Prostatakarzinom im fortgeschrittenen Stadium, sowohl bei unbehandelten als auch bei vorbehandelten Patienten.
Link zur Fachinformation des Compendium®
Link to MedlinePlus, a service of the U.S. National Library of Medicine, National Institutes of Health
Link to National Cancer Institute
Link zu Wiki
Link zu PharmaWiki
Link to Physicians Desk Reference (PDR)
Info for Patients presented by Scott Hamilton from Chemocare.com