Altretamine
| According to the NCI website Altretamine is a synthetic cytotoxic s-triazine derivative similar in structure to alkylating agent triethylenemelamin with antineoplastic activity. Although the precise mechanism by which altretamine exerts its cytotoxic effect is unknown, N-demethylation of altretamine may produce reactive intermediates which covalently bind to DNA, resulting in DNA damage. Indikationen/Anwendungsmöglichkeiten: Ovarian cancer Link to MedlinePlus, a service of the U.S. National Library of Medicine, National Institutes of Health Link to National Cancer Institute Link zu Wiki Link to Physicians Desk Reference (PDR) Info for Patients presented by Scott Hamilton from Chemocare.com Zytostatikum |