Seven important Presentations from the SABCS 2023 Press Briefings

  • Next-generation SERD Protects Against Progression in Some Patients With Advanced Breast Cancer Resistant to Standard Hormone Therapy
  • BRCA-mutation Carriers With a History of Early-onset Breast Cancer May Benefit From Risk-reducing Surgery
  • PARP Inhibition Shows Long-term Survival Benefits for Patients With High-risk, BRCA-positive Breast Cancer in OlympiA Trial
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Next-generation SERD Protects Against Progression in Some Patients With Advanced Breast Cancer Resistant to Standard Hormone Therapy

GS1-01: Imlunestrant, an Oral Selective Estrogen Receptor Degrader (SERD), as Monotherapy and Combined
with Abemaciclib, for Patients with ER+, HER2- Advanced Breast Cancer (ABC), Pretreated with Endocrine
Therapy (ET): Results of the Phase 3 EMBER-3 trial

More info about study

 

Recorded @ SABCS 2024, December 11
 

SLIDES Courtesy [Presenting Author]

Published in NEJM: Imlunestrant with or without Abemaciclib in Advanced Breast Cancer

 

BRCA-mutation Carriers With a History of Early-onset Breast Cancer May Benefit From Risk-reducing Surgery

GS1-08: Association between risk-reducing surgeries and survival in young BRCA carriers with breast
cancer: results from an international cohort study

More INFO about Study

Recorded @ SABCS 2023, December 6
 

SLIDES Courtesy Presenting Author

 
PARP Inhibition Shows Long-term Survival Benefits for Patients With High-risk, BRCA-positive Breast Cancer in OlympiA Trial

GS1-09: OlympiA- Phase 3, multicenter, randomized, placebo-controlled trial of adjuvant olaparib after
(neo)adjuvant chemotherapy in patients w/ germline BRCA1/BRCA2 pathogenic variants & high risk HER2-
negative primary breast cancer; longer term follow

More INFO about Study

Recorded @ SABCS 2023, December 7
 
Exercise May Boost Quality of Life for Patients With Metastatic Breast Cancer

GS02-10
Effects of a structured and individualized exercise program on fatigue and health-related quality
of life in patients with metastatic breast cancer: the multinational randomized controlled
PREFERABLE-EFFECT study

More INFO about Study

Recorded @ SABCS 2023, December 7

SLIDES Courtesy [Presenting Author: Anne M. May, PhD]

Patients with HR-positive Breast Cancer May Use Fertility Preservation and Assisted Reproductive Technologies Without Increased Risk of Recurrence

GS02-11
Fertility preservation and assisted reproductive technologies (ART) in breast cancer (BC) patients
(pts) interrupting endocrine therapy (ET) to attempt pregnancy

More INFO about Study

Recorded @ SABCS 2023, December 7

SLIDES Courtesy [Presenting Author: Hatem A. Azim, Jr., MD, PhD]

Skipping Adjuvant Radiotherapy May Not Impact Risk of Recurrence or Progression in Patients with Low-risk DCIS

GS03-01
Magnetic Resonance Imaging and a 12-Gene Expression Assay to Optimize Local Therapy for
Ductal Carcinoma In Situ: 5-year clinical outcomes of E411

More INFO about Study

Recorded @ SABCS 2023, December 8

SLIDES Courtesy [Presenting Author: Seema Khan, MD]

 

Some Breast Cancer Survivors May Safely De-escalate Mammography Three Years After Surgery

GS03-02
Mammographic surveillance in early breast cancer patients aged 50 years or over: results of the
Mammo-50 non-inferiority trial of annual versus less frequent mammograph

More INFO about Study

Recorded @ SABCS 2023, December 8

SLIDES Courtesy [Presenting Author: Janet A. Dunn, PhD]

 

Potentially Targetable Fusion RNAs May Be More Common in Metastatic Breast Cancer Than Previously Realized

GS03-09
Characterization and proposed therapeutic exploitation of fusion RNAs in metastatic breast
cancers

More INFO about Study

Recorded @ SABCS 2023, December 8

SLIDES Courtesy [Presenting Author: Nolan Priedigkeit, MD, PhD]

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